Posted: February 28th, 2023

Natural products Synthesis

Many  medicinal drugs come from natural resources such as plants, insects,  corals, etc. One typical example is the synthesis of the commonly known  as Non-steroidal anti-inflammatory, acetylsalicylic acid  (aspirin)  derived from  salicin the natural product isolated from the bark of the  willow tree Salix alba L.

In this post you are required to: 

PART A

Use Google Scholar to search for publications related to the topic. You can use either Plant based synthesis or Natural products Synthesis to start your search.

  • Select a paper that is related to the Synthesis of a Natural product.
  • Take  some time reading the information provided and Indicate the name of the  natural compound the natural resource for and the medicinal uses of the  compound. 
  • Use the name of the compound or the trade name to Search the chemical structure of this drug using MOLVIEW,  MolView
  • take a screenshot of the chemical structure of your molecule and edit the image  identifying and naming all functional groups.
  • Show  the total synthesis scheme (If available) and Circle or highlight the  steps of the synthesis you are familiar with (If any). 
  • If available explain to us how many steps the synthesis involved and how long did it take the research group to make this drug. 

NOTE: Please do not use Aspirin in your search.

PART B

Look at the video: Changing the drug pricing game

Respond to the following questions:

  • What is your stand regarding drug pricing  and the solutions proposed by the author Dr. Peter Bach
  • Do you think the price of drugs should be related with how difficult it is to be prepared?

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