Posted: March 12th, 2023

WH D7 response

APANo plagirism

· You should respond to at least two of your peers by extending, refuting/correcting, or adding additional nuance to their posts. Formatted and cited in current APA style with support from at least 1 academic sources. Your reply posts are worth

2 points

(1 point per response.) 

· All replies must be constructive and use literature where possible.

Case 2 (suzana)

The American College of Obstetricians and Gynecologist (ACOG) recommends in its guideline’s aspirin 81 mg daily. To which group of pregnant women do the ACOG recommend in its guideline’s aspirin 81 mg daily? 

To avoid or postpone the onset of preeclampsia, low-dose aspirin has been used throughout pregnancy. For women with a history of early-onset preeclampsia and preterm delivery at less than 34 weeks of gestation, or for women with more than one prior pregnancy complicated by preeclampsia, the American College of Obstetricians and Gynecologists recommended daily low-dose aspirin beginning in the late first trimester. Hypertensive disorders of pregnancy are a leading cause of maternal morbidity and mortality worldwide, accounting for more than 70,000 maternal deaths each year. Aspirin is an inexpensive and widely available drug that has the potential to safely help pregnant women and neonates (Van Doorn et al., 2021).

Caste Study #6 (Tania)

Discuss three fetal screening and include: screening test name, screening test component, gestational age to perform the test, what defect (s) will be screening.

Fetal screenings are performed on all pregnant women to determine whether there is a higher chance that the fetus may be suffering from a genetic condition. In the past, genetic testing in pregnancy used to be mostly focused on trisomy 21 (Down syndrome), but it is now able to identify a wide variety of genetic abnormalities. In the first trimester, between the 11th through 13th week of gestation, a nuchal translucency (NT) ultrasound is performed to view the subcutaneous fluid buildup behind the neck of the fetus. This exam is used to test for multiple congenital conditions. NT was primarily regarded as a marker of trisomies 21, 18, and 13, and Turner syndrome; however, increasing evidence suggests that abnormal NT measurements might also be related to other chromosomal abnormalities and genetic syndromes, structural anomalies, skeletal dysplasia, congenital infections, metabolic and hematologic disorders, and other rare conditions (Sahin Uysal et al., 2019).

In the second trimester of pregnancy, a quadruple test is conducted to detect for serious birth defects by assessing four chemistry components in the mother’s blood. The Beckman Access2 Immunoassay System is an automated analyzer that enables rapid measurement of alpha-fetoprotein, unconjugated estriol, human chorionic gonadotropin, and dimeric inhibin A (Tecleab et al., 2019). This test is simple and slightly invasive, giving doctors a better idea if there is a necessity of performing more delicate, precise, and frequently riskier diagnostic procedures.

The non-invasive prenatal (NIPT)screening test is done as early as nine weeks of pregnancy or as late as the time of birth. The NIPT test examines cell free fetal DNA in the mother’s blood and plasma that can detect fetal aneuploidies, limited fetal gene disorders and fetal nucleated cells in maternal circulation. More than 2 million NIPT exams have been performed to help with the detection of genetic defects. The test is more accurate than other forms of prenatal screening, with a sensitivity ranging from 90 to 99%, and specificity ranging from 99 to 100% depending on the condition (Cernat et al., 2020).